International Chemical Safety Cards 1,3,5-TRICHLOROBENZENE ICSC: 0344 sym-Trichlorobenzene C6H3Cl3 Molecular mass: 181.5 ICSC #    0344 CAS #     108-70-3 RTECS # DC2100100 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes). Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Redness. Pain. Safety spectacles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: P3 filter respirator for toxic particles). Separated from strong oxidants. Keep in a well-ventilated room. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0344 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 2002. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 1,3,5-TRICHLOROBENZENE ICSC: 0344 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: WHITE TO YELLOW CRYSTALS OR POWDER , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic and corrosive fumes. Reacts with oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes and the respiratory tract. Inhalation of the aerosol may cause lung oedema (see Notes). Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver, kidneys, nasal passage and thyroid gland , resulting in impaired functions or tissue lesions. PHYSICAL PROPERTIES Boiling point: 208°C Melting point: 63°C Solubility in water: none Vapour pressure, kPa at 78°C: 1.33 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0 Flash point: 107°C Octanol/water partition coefficient as log Pow: 4.15 ENVIRONMENTAL DATA This substance may be hazardous to the environment; special attention should be given to fish. In the food chain important to humans, bioaccumulation takes place, specifically in aquatic organisms. N O T E S Toxicology is based on 1,2,4-trichlorobenzene. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. ADDITIONAL INFORMATION ICSC: 0344 1,3,5-TRICHLOROBENZENE (C) IPCS, CEC, 2002

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